Neuroscience is growing rapidly, exploring unknown mechanisms involved in development of various brain diseases. Bioelectronics, on the other hand, suggests novel approaches for diagnosis and therapy of different types of diseases. Most of these approaches are not tuned for pre-clinical or clinical brain applications. Arami lab utilizes multidisciplinary and advanced knowledge of device fabrication, materials engineering and brain science to reshape the current bioelectronics-brain interfaces and develop new and clinically-needed micro- and nano-platforms with effective diagnostic and therapeutic functionalities in the brain microenvironment. The primary goal of our research group is to bridge this gap and generate advanced techniques for diagnosis and therapy of brain diseases.

Our initial research goals include:

(1) Engineering flexible bioelectronic interfaces for effective and expedited treatment of the brain diseases, especially those which are not treatable.

(2) Designing soft and flexible bioelectronic platforms for point-of-care and continuous monitoring of the brain vital parameters such as intracranial pressure and biochemical and electrical activities.

(3) Developing nano-platforms and micro-engineered interfaces for targeted diagnosis, therapy and controlling the diseases using optical, magnetic and ultrasound stimuli. 

As a long-term perspective, we envision that the outcomes of these projects will not be limited to brain and can be expanded to a wider range of diseases in a near future.