Publications
Nanomedicine for Spontaneous Brain Tumors: A Companion Clinical Trial
Remotely controlled near-infrared-triggered photothermal treatment of brain tumours in freely behaving mice using gold nanostars
Selected publications
Hamed Arami, S. Kananian, L. Khalifehzadeh, C. B. Patel, E. Chang, Y. Tanabe, Y. Zeng, S. Madsen, M. Mandella, R. Sinclair, A.S.Y. Poon, S.S. Gambhir, “Remotely controlled near-infrared-triggered photothermal treatment of brain tumours in freely behaving mice using gold nanostars”, Nature Nanotechnology, 17 (2022) 1015.
Q. Wei, Hamed Arami*, H. A. Santos, H. Zhang, Y. Li, J. He, D. Zhong, Y. Qiao, D. Ling, M. Zhou, “Intraoperative Assessment and Photothermal Ablation of the Tumor Margins Using Gold Nanoparticles”, Advanced Science, 8 (2021) 2002788. {* co-first author}
Hamed Arami, C. B. Patel, S. J. Madsen, P. Dickinson, R. M. Davis, Y. Zeng, B. K. Sturges, K. Woolard, F. G. Habte, D. Akin, R. Sinclair, S. S. Gambhir, “Nanomedicine for Spontaneous Brain Tumors: A Companion Clinical Trial”, ACS Nano, 13 (2019) 2858-69. {selected for journal cover}
H. Arami, E. Teeman, A. Troksa, H. Bradshaw, K. Saatchi, A. Tomitaka, S. S. Gambhir, U. Hafeli, D. Liggitt, K. M. Krishnan, “Tomographic Magnetic Particle Imaging of Cancer Targeted Nanoparticles”, Nanoscale, 9 (2017) 18723-18730.
Full List:
2022:
Hamed Arami, S. Kananian, L. Khalifehzadeh, C. B. Patel, E. Chang, Y. Tanabe, Y. Zeng, S. Madsen, M. Mandella, R. Sinclair, A.S.Y. Poon, S.S. Gambhir, “Remotely controlled near-infrared-triggered photothermal treatment of brain tumours in freely behaving mice using gold nanostars”, Nature Nanotechnology, 17 (2022) 1015.
2021:
Q. Wei, Hamed Arami*, H. A. Santos, H. Zhang, Y. Li, J. He, D. Zhong, Y. Qiao, D. Ling, M. Zhou, “Intraoperative Assessment and Photothermal Ablation of the Tumor Margins Using Gold Nanoparticles”, Advanced Science, 8 (2021) 2002788. {* co-first author}
S.Y. Hua, S. Zhong, Hamed Arami*, J. He, D. Zhong, D. Zhang, X. Chen, J. Qian, X. Hu, M. Zhou, “Simultaneous Deep Tracking of Stem Cells by Surface Enhanced Raman Imaging Combined with Single-Cell Tracking by NIR-II Imaging in Myocardial Infarction”, Advanced Functional Materials, 31 (2021) 2100468. {* co-first author}
2020:
L. Tadesse, C. Ho, D. H. Chen, Hamed Arami, N. Banaei, S. S. Gambhir, S. Jeffrey, A. Saleh, J. Dionne, “Plasmonic and Electrostatic Interactions Enable Uniformly-enhanced Liquid Bacterial Surface-enhanced Raman Scattering (SERS)”, Nano Letters, 20 (2020) 7655.
R.*Khalifehzadeh, Hamed Arami*, “Biodegradable Calcium Phosphate Nanoparticles for Cancer Therapy”, Advances in Colloid and Interface Science, 279 (2020) 102157. {* co-first author}
A. Tomitaka, Hamed Arami, A. Ahmadivand, B. Gerislioglu, N. Pala, A. McGoron, Y. Takemura, M. Febo, N. Madhavan, “Magneto-plasmonic Nanostars for Image-guided and NIR-triggered Drug Delivery”, Scientific Reports, 10 (2020) 10115.
R. Khalifehzadeh, Hamed Arami*, “The CpG Molecular Structure Controls Mineralization of Calcium Phosphate Nanoparticles and their Immunostimulation Efficacy as Vaccine Adjuvants”, Nanoscale, 12 (2020) 9603-9615. {* co-first author}
2019:
Hamed Arami, C. B. Patel, S. J. Madsen, P. Dickinson, R. M. Davis, Y. Zeng, B. K. Sturges, K. Woolard, F. G. Habte, D. Akin, R. Sinclair, S. S. Gambhir, “Nanomedicine for Spontaneous Brain Tumors: A Companion Clinical Trial”, ACS Nano, 13 (2019) 2858-69. {selected for journal cover}
R. Khalifehzadeh, Hamed Arami, “DNA-templated Strontium-doped Calcium Phosphate Nanoparticles for Gene Delivery in Bone Cells”, ACS Biomaterials Science and Engineering, 5 (2019) 3201-11.
2018:
E. Chang, C. B. Patel, C. Pohling, C. Young, J. Song, T. A. Flores, Y. Zeng, L. Joubert, Hamed Arami, A. Natarajan, B. Sinclair, S. S. Gambhir, “Tumor Treating Fields Increases Membrane Permeability in Glioblastoma Cells”, Cell Death Discovery, 4 (2018) 113.
P. P. Tripathi, H. Arami, I. Banga, J. Gupta, S. Gandhi, “Cell Penetrating Peptides in Preclinical and Clinical Cancer Diagnosis and Therapy”,Oncotarget, 9 (2018) 37252-67.
O. Vermesh, A. Aalipour, T. J. Ge, Y. Saenz, Y. Guo, I. S. Alam, S. Park, C. N. Adelson, Y. Mitsutake, J. Vilches-Moure, E. Godoy, M. H. Bachmann, C. C. Ooi, J. K. Lyons, K. Mueller, H. Arami, A. Green, E. I. Solomon, S. X. Wang, S. S. Gambhir, “An Intravascular Magnetic Wire for the High-throughput Retrieval of Circulating Tumour Cells In Vivo”, Nature Biomedical Engineering, 2 (2018) 696-705.
A. Tomitaka, H. Arami, Z. Huang, A. Raymond, E. Rodriguez, Y. Cai, M. Febo, Y. Takemura, N. Madhavan, “Hybrid Magneto-plasmonic Liposomes for Multimodal Image-guided and Brain-targeted HIV Treatment”, Nanoscale, 10 (2018) 184-194.
2017:
H. Arami, E. Teeman, A. Troksa, H. Bradshaw, K. Saatchi, A. Tomitaka, S. S. Gambhir, U. Hafeli, D. Liggitt, K. M. Krishnan, “Tomographic Magnetic Particle Imaging of Cancer Targeted Nanoparticles”, Nanoscale, 9 (2017) 18723-18730.
A. Tomitaka, H. Arami, Y. Takemura, M. Nair, “Image-Guided Therapy”, Advances in Personalized Nanotherapeutics, (2017) 41-55.
A. Tomitaka, H. Arami, A. Raymond, A. Yndart, A. Kaushik, R. Jayant, Y. Takemura, Y. Cai, M. Nair, “Development of Magneto-plasmonic Nanoparticles for Multimodal Image-guided Therapy to the Brain”, Nanoscale, 9 (2017) 764-773.
2016:
S. Gandhi, H. Arami, K. M. Krishnan, “Detection of Cancer-specific Proteases Using Magnetic Relaxation of Peptide-conjugated Nanoparticles in Biological Environment”, Nano letters, 16 (2016), 3668-3674.
L. R. Croft, P. W. Goodwill, J. J. Konkle, H. Arami, D. A. Price, A. X. Li, E. U. Saritas, S. M. Conolly, “Low drive field amplitude for improved image resolution in magnetic particle imaging”, Medical Physics, 43 (2016) 424-435.
N. Poudyal, K. Gandha, J. Liu, K. Elkins, H. Arami, J P. Liu “Ferromagnetic FePt/Au Core/Shell Nanoparticles Prepared by Solvothermal Annealing”, IEEE Magnetics Letters, 7 (2016) 4102105.
2015:
H. Arami, A. Khandhar, D. Liggitt, K. M. Krishnan “In Vivo Delivery, Pharmacokinetics, Biodistribution and Toxicity of Iron Oxide Nanoparticles”, Chemical Society Reviews, 44 (2015) 8576-8607.
A. Tomitaka, H. Arami, S. Ghandi, K. M. Krishnan, “Lactoferrin conjugated iron oxide nanoparticles for targeting brain glioma cells in magnetic particle imaging”, Nanoscale, 7 (2015) 16890-16898.
R. M. Ferguson, A. P. Khandhar, S. Kemp, H. Arami, E. U. Saritas, L. R. Croft, P. W. Goodwill, A. Halkola, J. Rahmer, S. M. Conolley, K. M. Krishnan, “Magnetic Particle Imaging with Safe, Tailored Iron Oxide Nanoparticle Tracers”, IEEE Transactions on Medical Imaging, 34 (2015) 1077-1084.
H. Arami, A. P. Khandhar, A. Tomitaka, P. W. Goodwill, E. Yu, S. M. Conolley, K. M. Krishnan, “In vivo Multimodal Magnetic Particle Imaging (MPI) with Tailored Magneto/Optical Contrast Agents”, Biomaterials, 52 (2015) 251-261.
R. Hufschmid, H. Arami, E. Teeman, M. Ferguson, M. Gonzales, K. M. Krishnan “Synthesis of Phase-pure Iron Oxide Nanoparticles by Thermal Decomposition”, Nanoscale, 7 (2015) 11142-11154.
A. Khandhar, R. M. Ferguson, H. Arami, S. J. Kemp, K. M. Krishnan, “Tuning Surface Coatings of Optimized Magnetite Nanoparticle Tracers for In-vivo Magnetic Particle Imaging”, IEEE Transactions on Magnetics, 51 (2015) 1-4.
J. W.M. Bulte, P. Walczak, M. Janowski, K. M. Krishnan, H. Arami, A. Halkola, B. Gleich, J. Rahmer “Quantitative “Hot-Spot” Imaging of Transplanted Stem Cells Using Superparamagnetic Tracers and Magnetic Particle Imaging”, Tomography, 1 (2015) 91-97.
R. Hufschmid, H. Arami, K.M. Krishnan, ND Browning, “Ex Situ and In Situ (S)TEM of Iron Oxide Nanoparticles Synthesized by Decomposition of an Organometallic Precursor”, Microscopy and Microanalysis, 21 (2015), 965-966.
2014:
H. Arami, K. M. Krishnan, “Intracellular Performance of Tailored Nanoparticle Tracers in Magnetic Particle Imaging”, Journal of Applied Physics, 115 (2014) 17B306.
M. Gould, R. Barnour, N. Thomas, H. Arami, K. M. Krishnan, K. M. Fu, “Room-temperature Detection of a Single 19nm Super-paramagnetic Nanoparticles with an Imaging Magnetometer”, Applied Physics Letters, 105 (2014) 072406.
F. Ludwig, H. Remmer, C. Kuhlmann, T. Wawrzik, H. Arami, R. M. Ferguson, K. M. Krishnan, “Magnetic Properties of Single Core Magnetite Tracers Optimized for Magnetic Particle Imaging”, Journal of Magnetism and Magnetic Materials, 360 (2014) 169-173.
2013:
T. Wang, F. M. Kievit, O. Veiseh, H. Arami, Z. Stephen, C. Fang, Y. Liu, R. G. Ellenbogen, M. Zhang, “Targeted Cell Uptake of a Non-internalizing Antibody through Conjugation to Iron Oxide Nanoparticles in Primary Central Nervous System Lymphoma”, World Neurosurgery, 80 (2013) 134-141.
R. M. Ferguson, A. P. Khandhar, H. Arami, L. Hua, O. Hovorka, K. M. Krishnan, “Tailoring the Magnetic and Pharmacokinetic Properties of Iron Oxide MPI Tracers”, Biomedical Engineering, 58 (2013) 493-507.
H. Arami, R. M. Ferguson, A. P. Khandhar, K. M. Krishnan, “Size-dependent Ferrohydrodynamic Relaxometry of Magnetic Particle Imaging Tracers in Different Environments”, Medical Physics, 40 (2013) 071904.
H. Arami, K. M. Krishnan, “Highly Stable Amine Functionalized Iron Oxide Nanoparticles Designed for Magnetic Particle Imaging (MPI)”, IEEE Transactions on Magnetics, 49 (2013) 3500-3503
A. P. Khandhar, R. M. Ferguson, H. Arami, K. M. Krishnan, “In-vivo Characterization of Magnetic Nanoparticle Tracers Using Magnetic Particle Spectrometry”, Biomaterials, 34 (2013) 3837-3845.
2012:
F. M. Kievit, Z. Stephen, O. Veiseh, H. Arami, T. Wang, J. Park, V. Phan-Lai, M. L. Disis, M. Zhang, “Targeting of Primary Breast Cancers and Metastases in a Transgenic Mouse Model Using Rationally Designed Multifunctional SPIONs”, ACS Nano, 6 (2012) 2591-2601.
2011:
O. Veiseh, F. M. Kievit, H. Mok, J. Ayesh, C. Clark, C. Fang, M. Leung, H. Arami, J. O. Park, M. Zhang, “Cell Transcytosing Poly-arginine Coated Magnetic Nanovector for Safe and Effective siRNA Delivery”, Biomaterials, 32 (2011) 5717-5725.
H. Arami, Z. Stephen, O. Veiseh, M. Zhang, “Chitosan Coated Iron Oxide Nanoparticles for Molecular Imaging and Drug Delivery“, Advances in Polymer Science, 243 (2011) 163-184.
2009:
K. Yano, V. Nandwana, G. S. Chaubey, N. Poudyal, S. Kang, H. Arami, J. Griffis, J. P. Liu, “Synthesis and Characterization of Magnetic FePt/Au Core/Shell Nanoparticles”, Journal of Physical Chemistry C, 113 (2009) 13088–13091.
H. Arami, M. Mohajerani, R. Khalifehzadeh, A. Lak, S. K. Sadrnezhaad, “Rapid Formation of Hydroxyapatite Nanostrips via Microwave Irradiation”, Journal of Alloys and Compounds, 469 (2009) 391-394.
M. Mazloumi, S. Taghavi, H. Arami, S. Zanganeh, A. Kajbafvala, M. R. Shayegh, S.K. Sadrnezhaad, “Self-assembly of ZnO Nanoparticles and Subsequent Formation of Hollow Microspheres”, Journal of Alloys and Compounds, 468 (2009) 303-307.
H. Arami, R. Khalifehzadeh, H. Keivan, F. Khomamizadeh, “Effect of Pre-deformation and Heat Treatment Conditions in the SIMA Process on Microstructural and Mechanical Properties of A319 Alloy”, Journal of Alloys and Compounds, 468 (2009) 130-135.
H. Arami, M. Mazloumi, R. Khalifehzadeh, S. K. Sadrnezhaad, “Self Assembled Nanostructure ZnO Hollow Spheres with UVA Luminescence”, Advances in Applied Ceramics: Structural, Functional and Bioceramics, 108 (2009) 73-77.
2008:
A. Lak, M. Mazloumi, M. S. Mohajerani, S. Zanganeh, M. Shayegh, A. Kajbafvala, H. Arami, S. K. Sadrnezhaad, “Rapid Formation of Monodispersed Hydroxyapatite Nanorods with Narrow-size Distribution via Microwave Irradiation”, Journal of the American Ceramics Society, 91 (2008) 3580-3584.
A. Lak, M. Mazloumi, M. Mohajerani, A. Kajbafvala, S. Zanganeh, H. Arami, S. K. Sadrnezhaad, “Self-assembly of Dandelion-Like Hydroxyapatite Nanostructures via Hydrothermal Method”, Journal of the American Ceramics Society, 91 (2008) 3292-3297.
H. Arami, A. Simchi and S.M. Seyed Reihani, “Mechanical Induced Reaction in Al-CuO System for In-situ Fabrication of Al Based Nanocomposites”, Journal of Alloys and Compounds, 465 (2008) 151-156.
H. Arami, M. Mazloumi, R. Khalifehzadeh, S. K. Sadrnezhaad, “Surfactant Free Hydrothermal Formation of Pb3O4 Nanorods”, Journal of Alloys and Compounds, 466 (2008)323-325.
M. Torabi, R. Khalifehzadeh, H. Arami, S. K. Sadrnezhaad, “Electrochemical Deposition of Flower-like Nickel Nanostructures on Well-defined n-Si(111):H”, International Journal of Engineering, 21 (2008) 177-182.
H. Arami, M. Mazloumi, R. Khalifehzadeh, S. K. Sadrnezhaad, “Bundles of Self Assembled Boehmite Nanostrips from a Surfactant Free Hydrothermal Route”, Journal of Alloys and Compounds, 461 (2008)551-554.
H. Arami, R. Khalifehzadeh, F. Khomamizadeh, “Microporosity Control and Thermal-Fatigue Performance of A319 Aluminum Foundry Alloy”, Materials Science and Engineering A, 472 (2008) 107-114.
2007:
H. Arami, M. Mazloumi, R. Khalifehzadeh, S. K. Sadrnezhaad, “Dahlia-like Cadmium Hydrogen Phosphate Hydrate Nanostructures as Templates for Prismatic Cadmium Hydroxyapatite Hexagons”, Crystal Growth, 309 (2007) 37-42.
H. Arami, M. Mazloumi, R. Khalifehzadeh, S. K. Sadrnezhaad, “Electron Beam Induced “Nanocalcination“ of Boehmite Nanostrips to Mesoporous α-alumina phase”, Journal of American Ceramic Society, 90 (2007) 3311-3313.
S. Shahandeh, H. Arami, S. K. Sadrnezhaad, “Interfacial Energy Determination of Nano-scale Precipitates by CALPHAD Description of Gibbs-Thomson Effect”, Journal of Materials Science, 42 (2007) 9440–9446.
H. Arami, M. Mazloumi, R. Khalifehzadeh, S. K. Sadrnezhaad, “Sonochemical Preparation of TiO2 Nanoparticles”, Materials Letters, 61 (2007) 4559-4561.
H. Arami, M. Mazloumi, R. Khalifehzadeh, S. K. Sadrnezhaad, “Polypyrrole/multiwall Carbon Nanotube Nanocomposites Electropolymerized on Copper Substrate”, Materials Letters, 61 (2007) 4412-4415.
R. Khalifehzadeh, S. Forouzan, H. Arami, S.K. Sadrnezhaad, “Prediction of the Effect of Vacuum Sintering Conditions on Porosity Content and Hardness of NiTi Shape Memory Alloy Using ANFIS”, Computational Materials Science, 40 (2007) 359-365.
M. Mazloumi, H. Arami, R. Khalifehzadeh, S.K. Sadrnezhaad, “Studies on Synthesis of Alumina Nanopowders from Synthetic Bayer Liquor”, Materials Research Bulletin, 42 (2007) 1004-1009.
H. Arami, A. Simchi, “Reactive Milling Synthesis of Nanocrystalline Al-Cu/Al2O3 Nanocomposite”, Materials Science and Engineering A, 464 (2007) 225-232.
2006:
M. Mazloumi, H. Arami, R. Khalifehzadeh, S. K. Sadrnezhaad, “Alumina Nanopowder Production from Synthetic Bayer Liquor”, Journal of American Ceramics Society, 89 (2006) 3654-3657.
S.K. Sadrnezhad, H. Arami, H. Keivan, R. Khalifehzadeh, “Powder Metallurgical Fabrication and Characterization of Nanostructure Porous NiTi Shape Memory Alloy”, Materials and Manufacturing Processes, 21 (2006) 727-735.
A. Eftekhari, F. Molaei, H. Arami, “Flower-like Bundles of ZnO Nanosheets as an Intermediate between Hollow Nanospheres and Nanoparticles”, Materials Science and Engineering A, 437 (2006) 446-450.